Michael L. Robinson

The paper identifies a developmental wave of programmed ganglion cell death in human retinal organoids, showing it occurs via the extrinsic apoptotic pathway.

The paper investigates the role of miR-26 in lens development and finds that its deficiency leads to adult-onset cataract through transcriptome alterations.

This study identifies FGF's role in regulating Rho and Rac activity to drive lens fiber cell elongation and migration during differentiation.

The paper creates a single-cell multiomic atlas of lens development, identifying regulatory mechanisms and cataract-linked networks through snRNA-seq, snATAC-seq, and CUT&RUN-seq.

The paper describes a CRISPR/Cas9 strategy to generate a hiPSC line with fluorescent reporters for three retinal cell types, enabling real-time monitoring during organoid development.