Young-Cho Kim

This study shows that prefrontal neuronal ramping and theta activity occur during both freely-moving and head-fixed interval timing tasks in mice, suggesting they are features of temporal behavior rather than specific motor programs.

This study shows that loss of ASIC1A in the basolateral amygdala increases CO2-evoked jumping and reduces freezing in mice.

This study shows that VTA dopamine neurons control timing variability in Parkinson's disease by modulating neural activity during interval timing tasks.

This study shows that social context and dopamine signaling interact in Drosophila mushroom bodies to regulate impulsivity, with MB neurons mediating this interaction.

This study shows D2-MSNs and D1-MSNs have opposing dynamics but complementary roles in interval timing, revealing how striatal pathways contribute to cognitive timing.

The paper generates and validates a Drd1-Flpo knock-in mouse line that expresses Flp recombinase specifically in D1DR+ neurons, enabling intersectional genetic studies of these neurons.

This study shows amphetamine increases timing variability by reducing prefrontal cortex ramping activity and neural interactions in mice.

The paper shows that with experience, striatal neurons improve temporal decoding and exhibit experience-related changes in activity patterns during interval timing tasks in mice.

The paper examines how neuronal ensembles in the medial frontal cortex and dorsomedial striatum change during temporal learning in rodents.

This study shows that stimulating corticostriatal pathways compensates for medial frontal cortex inactivation, improving interval timing behavior in mice.

This study investigates how scopolamine affects interval timing in mice by examining changes in medial frontal cortex activity, finding that it impairs timing but does not alter time-related ramping.

The paper investigates the role of prefrontal D1 dopamine-receptor neurons in interval timing using optogenetics and finds that delta-frequency coherence and early stimulation improve timing performance in dopamine-depleted animals.