Emmanuelle Szenker‐Ravi

This study shows that loss of IVNS1ABP causes a progeroid neuropathy by impairing proteostasis, leading to protein aggregation and lysosomal dysfunction in neuronal cells.

The paper identifies MMP21 as a morphogen transported by leftward fluid flow to specify left-sided development in Xenopus embryos, revealing its role in heterotaxy.

The paper identifies R-SPONDIN2-expressing mesenchymal cells as a niche for lung bud tip progenitors using single-cell RNA sequencing and functional experiments.

This study shows that RSPO1 and RSPO3 are essential for WNT/β-catenin signaling in kidney development, with their deletion causing loss of renal progenitors and failure of MET.