Author

Alexis S. Fine

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Ansley S. ConcholaiD· 2 shared Emily M. HollowayiD· 2 shared Jason R. SpenceiD· 2 shared Renee F. C. HeiniD· 2 shared Tristan FrumiD· 2 shared Yu-Hwai Tsai· 2 shared Alyssa J. MilleriD· 1 shared Angeline WuiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersDevelopmental Biology

Ansley S. ConcholaORCID

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2 papers

Recent·Most cited

Stable iPSC-derived NKX2-1+ Lung Bud Tip Progenitor Organoids Give Rise to Airway and Alveolar Cell Types

Renee F. C. Hein, Ansley S. Conchola, Alexis S. Fine, Zhiwei Xiao, Tristan Frum, Lindy K. Brastrom, Mayowa A. Akinwale, Charlie J. Childs, Yu-Hwai Tsai, Emily M. Holloway, Sha Huang, John E. Mahoney, Idse Heemskerk, Jason R. Spence

This study develops iPSC-derived lung bud tip progenitor organoids that can be expanded and differentiated into airway or alveolar organoids, showing transcriptional similarity to in vivo progenitors.

Development · Aug 30, 2022Peer-reviewedDevelopmental Biology

R-SPONDIN2+ Mesenchymal Cells Form the Bud Tip Progenitor Niche During Human Lung Development

Renee F. C. Hein, Joshua H. Wu, Emily M. Holloway, Tristan Frum, Ansley S. Conchola, Yu-Hwai Tsai, Angeline Wu, Alexis S. Fine, Alyssa J. Miller, Emmanuelle Szenker‐Ravi, Kelley S. Yan, Calvin Jay Kuo, Ian A. Glass, Bruno Reversade, Jason R. Spence

The paper identifies R-SPONDIN2-expressing mesenchymal cells as a niche for lung bud tip progenitors using single-cell RNA sequencing and functional experiments.

Developmental Cell · Jun 8, 2022Peer-reviewedDevelopmental Biology