Author

Elsie C. Jacobson

University of AucklandORCID 0000-0002-6094-5490Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 3 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:Hi-C· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Donald E. OlinsiD· 3 shared Jo Kate PerryiD· 3 shared Justin Martin O'SullivaniD· 3 shared Mark Hedley VickersiD· 3 shared Ada L. OlinsiD· 2 shared Amander T. ClarkiD· 1 shared Antuca Callejas-MaríniD· 1 shared Auriana Arabpour· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersGenomics

Donald E. OlinsORCID

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4 papers

Recent·Most cited

TFAP2A+ embryonic progenitor cells undergo fate diversification to give rise to human amnion, germline, and mesoderm

Auriana Arabpour, Jonathan DiRusso, Qiu Ya Wu, Mark Larsen, Young Sun Hwang, Elsie C. Jacobson, Thi Xuan Ai Pham, Nicole Agranonik, Megan Sparrow, Vernon Monteiro, Zenya Rebecca Bian, Nicolás Peláez, Antuca Callejas-Marín, Vincent Pasque, Kathrin Plath, Amander T. Clark

The paper shows that TFAP2A+ progenitor cells generate amnion, germline, and mesoderm through BMP signaling and basement membrane cues in vitro.

bioRxiv · Jun 26, 2025 · PreprintDevelopmental Biology

TNF-α differentially regulates cell cycle genes in promyelocytic and granulocytic HL-60/S4 cells

Elsie C. Jacobson, Lekha Jain, Jo Kate Perry, Mark Hedley Vickers, Donald E. Olins, Justin Martin O'Sullivan

This study shows TNF-α induces different cell cycle gene responses in promyelocytic and granulocytic HL-60/S4 cells, with promyelocytes showing upregulation and granulocytes downregulation, and granulocytes shifting towards a macrophage-like transcriptome.

G3 Genes Genomes Genetics · Jul 1, 2019Peer-reviewedGenomics

Hi-C detects novel structural variants in HL-60 and HL-60/S4 cell lines

Elsie C. Jacobson, Ralph Stefan Grand, Jo Kate Perry, Mark Hedley Vickers, Ada L. Olins, Donald E. Olins, Justin Martin O'Sullivan

The paper uses Hi-C and RNA-seq to identify and compare structural variants in HL-60 and HL-60/S4 cell lines, finding novel SVs and differences in their stability.

Genomics · May 13, 2019Peer-reviewedGenomics

Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells

Elsie C. Jacobson, Jo Kate Perry, David S. Long, Ada L. Olins, Donald E. Olins, Bryon E. Wright, Mark Hedley Vickers, Justin Martin O'Sullivan

The paper shows that neutrophil migration through small pores disrupts inactive chromatin organization, as revealed by transcriptomic and Hi-C analyses.

BMC Biology · Nov 26, 2018Peer-reviewedGenomics