Author

Tuan M. Nguyen

Broad InstituteORCID 0000-0003-4879-3962Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. S. M. WaliullahiD· 1 shared Andrew Pan· 1 shared Barbara DziegielewskaiD· 1 shared Bon Q. TrinhiD· 1 shared Daniel Geoffrey TeneniD· 1 shared Jeffrey Craig· 1 shared John G. ClohessyiD· 1 shared Junyan ZhangiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

A. S. M. WaliullahORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 19, 2025

An integrated DNA interactome and transcriptome profiling reveals a PU.1/enhancer RNA-mediated Feed-forward Regulatory Loop Regulating monocyte/macrophage development and innate immune functions

A. S. M. Waliullah, Kevin Qiu, Barbara Dziegielewska…·Bon Q. Trinh

This study identifies a PU.1/LOUP feed-forward regulatory loop that promotes monocyte/macrophage differentiation and innate immune functions through enhancer RNA-mediated mechanisms.

DOI 10.1101/2025.02.19.638695

humanChIP-seq

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Molecular BiologyGenome biologyPeer-reviewedJan 21, 2021

Optimized RNA-targeting CRISPR/Cas13d technology outperforms shRNA in identifying essential circRNAs

Yang Zhang, Tuan M. Nguyen, Xiao-Ou Zhang…·Pier Paolo Pandolfi

This study compares shRNA and CRISPR/Cas13d screens for circRNA function, finding that optimized CRISPR/Cas13d reduces false positives and identifies true functional circRNAs.

165 citationstop 1%

CRISPR screenexperimental assay

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