Author

Danilo Guerini

Novartis Institutes for BioMedical ResearchORCID 0000-0003-4976-0898Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Amandine Rietsch· 1 shared Andreas Hofmann· 1 shared Andrew I. MorrisoniD· 1 shared Benedikt GoretzkiiD· 1 shared Christian N. ParkeriD· 1 shared Damien Begue· 1 shared Débora BonenfantiD· 1 shared Delphine Jeanpierre· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Amandine Rietsch

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 8, 2023

A novel HERC4-dependent glue degrader targeting STING

Merve Mutlu, Isabel Schmidt, Andrew I. Morrison…·Danilo Guerini

This paper identifies AK59 as a molecular glue degrader for STING, showing HERC4 is the key E3 ligase for its degradation and demonstrating efficacy against STING mutations.

DOI 10.1101/2023.02.08.527642

humanexperimental assay

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