NeurosciencebioRxivPreprint
Loss of NudE-mediated dynein activation at synaptic terminals causes progressive axon length-dependent neurodegeneration
Zeeshan Mushtaq, Dario A. Lasser, Lena Maria Lion…·Jan Pielage
DOI 10.64898/2026.04.12.717987
Author
Leibniz-Forschungsinstitut für Molekulare PharmakologieORCID 0000-0003-4993-0340Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Zeeshan Mushtaq, Dario A. Lasser, Lena Maria Lion…·Jan Pielage
Fiorella Mazzone, Gina Gräßle, Zuzana Štorchová…·Tanja Maritzen
The paper identifies stress-induced changes in the surfaceome, revealing osmotic stress causes surface accumulation of CI-M6PR through reduced endocytosis and increased lysosomal exocytosis.
Marijn Kuijpers, Gaga Kochlamazashvili, Alexander Stumpf…·Volker Haucke
This study shows that neuronal autophagy regulates axonal ER calcium stores to control neurotransmission and postnatal viability in mice.