Viviane Praz

This study shows ALK variants differentially affect neuroblastoma tumor behavior and transcriptome depending on the cellular context.

This study induces in vivo reprogramming in C. elegans and finds it leads to heterogeneous effects on lifespan depending on developmental stage.

This paper develops an aging clock using chromatin accessibility data from PBMCs and shows it correlates with transcriptional changes during aging.

This study shows MAF1 represses RNA polymerase III transcription in mice, affecting nucleotide demand and metabolism across fasting and refeeding conditions.

This study shows HCF-2 inhibits cell proliferation and activates differentiation gene programs, distinct from its paralog HCF-1.

This study compares gene expression and epigenetic changes in mouse livers after partial hepatectomy and sham surgery, showing similar early responses but distinct later gene regulation patterns specific to regeneration.