Author

Niklas Dienstbier

Düsseldorf University HospitalORCID 0009-0000-0871-9165Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Melina VogtiD· 2 shared Prof. Dr. Holger GohlkeiD· 2 shared Sanil BhatiaiD· 2 shared Annabelle Friedrich· 1 shared Arndt BorkhardtiD· 1 shared Beate Lungerich· 1 shared Björn StorkiD· 1 shared Céline David· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Melina VogtORCID

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2 papers

Recent·Most cited

Cell BiologyCell Death and DiseasePeer-reviewedDec 23, 2025

Small-molecule inhibitor of C-terminal HSP90 dimerization modulates autophagy and functions synergistically with mTOR inhibition to kill cisplatin-resistant cancer cells

Céline David, Yadong Sun, Vitalij Woloschin…·Björn Stork

This paper introduces a C-terminal HSP90 dimerization inhibitor, VWK147, which induces cell death in cisplatin-resistant cancer cells and synergizes with mTOR inhibition to enhance therapeutic efficacy.

7 citations

humanproteomics

𝕏 PostBluesky

Pharmacology & ToxicologyScientific ReportsPeer-reviewedMay 21, 2025

Identification of non-charged 7.44 analogs interacting with the NHR2 domain of RUNX1-ETO and exhibiting an improved, selective antiproliferative effect in RUNX-ETO positive cells

Mohanraj Gopalswamy, David Bickel, Niklas Dienstbier…·Holger Gohlke

The paper identifies non-charged analogs of the inhibitor 7.44 that show improved antiproliferative effects against RUNX1-ETO positive cells.

1 citation

humanproteomics

𝕏 PostBluesky