ImmunologybioRxivPreprint
Inhibition of formate production blocks CD8+ T-cell responses and delays disease onset in a mouse model of type 1 diabetes
Erika Gabriela Ramirez-Hernandez, Micah Bell, Byung Soo Kong…·Nora Kory
This study shows that inhibiting formate production in CD8+ T cells delays type 1 diabetes onset in mice by reducing their activation and effector function.
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