Author

Darija Šoltić

UCL Queen Square Institute of NeurologyORCID 0009-0000-3151-6016Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Benjamin J. O’CallaghaniD· 2 shared Hannah J Lucas-ClarkeiD· 2 shared Hélène Plun‐FavreauiD· 2 shared James R. EvansiD· 2 shared Katharina CoskeriD· 2 shared Sonia GandhiiD· 2 shared Alex GriffithsiD· 1 shared Alexis PenverneiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersNeuroscience

Benjamin J. O’CallaghanORCID

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2 papers

Recent·Most cited

NeuroscienceAutophagy ReportsPeer-reviewedJun 12, 2026

Glucose concentration of neuronal media formulations influences PINK1-dependent mitophagy in human iNeurons

Benjamin J. O’Callaghan, Daniela Melandri, Darija Šoltić…·Hélène Plun‐Favreau

This study shows that glucose levels in neuronal culture media affect PINK1-dependent mitophagy in human iNeurons, with BrainPhys medium reducing mitophagy compared to N2B27.

1 citation

humanbulk RNA-seq

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NeurosciencebioRxivPreprintOct 13, 2025

The SNCA A53T mutation sensitizes human neurons and microglia to ferroptosis

Laura Mahoney‐Sanchez, Hannah J Lucas-Clarke, Alexis Penverne…·Sonia Gandhi

This study shows that the SNCA A53T mutation increases vulnerability to ferroptosis in neurons and microglia, suggesting 15-LO inhibition as a potential therapeutic target for Parkinson's disease.

1 citation

humanproteomics

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