Developmental BiologybioRxivPreprint
Imp1 acts as a dosage- and stage-dependent temporal rheostat orchestrating radial glial fate transitions and cortical morphogenesis
Romie Angelo G Azur, Daniel Feliciano, Isabel Espinosa-Medina…·Tzumin Lee
This study shows Imp1 regulates temporal fate transitions in radial glia during cortical development, affecting neuronal identity and spatial organization through dosage and stage-dependent mechanisms.
DOI 10.1101/2025.11.18.688993