Author

Miguel Marques Simoes-da-Silva

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do PortoORCID 0009-0000-4275-5733Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

André OliveiraiD· 1 shared Andrea MusacchioiD· 1 shared Arianna Esposito Verza· 1 shared Carlos CondeiD· 1 shared Cláudio E. SunkeliD· 1 shared Inês Mendes PintoiD· 1 shared Jakob NilssoniD· 1 shared Joana DuroiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

André OliveiraORCID

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1 paper

Recent·Most cited

Cell BiologyCurrent BiologyPeer-reviewedOct 22, 2025

POLO kinase inhibits Protein Phosphatase 1 to promote the Spindle Assembly Checkpoint and prevent aneuploidy

Margarida Moura, João Barbosa, Inês Mendes Pinto…·Carlos Conde

This study shows POLO kinase phosphorylates PP187B to inhibit its interaction with MPS1, maintaining SAC activity and preventing aneuploidy during mitosis.

2 citations

Drosophilaproteomics

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