Michela Ascolani

This study shows that LBR nucleoplasmic domains regulate X-chromosome solubility and nuclear organization during neural differentiation in mouse cells.

This study identifies TRIM66 as a key factor enforcing monogenic expression of olfactory receptors through epigenetic silencing of super-enhancers, impacting axonal projections and behavior.

This study shows that reducing OGT activity in mice causes embryonic lethality proportional to the reduction in O-GlcNAc modification, with milder reductions causing developmental delays and retrovirus activation.