Author

Gianna Sagona

University of IowaORCID 0009-0000-5103-8189Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aidan Freshly· 2 shared ANAMIKA VIKRAM· 2 shared Claudia Jun· 2 shared Lucy Kim· 2 shared Siming LiuiD· 2 shared Spencer J. PeacheeiD· 2 shared Syreine Richtsmeier· 2 shared Yumi ImaiiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Aidan Freshly

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell BiologyDiabetesPeer-reviewedMay 28, 2026

ALPHA/BETA HYDROLASE DOMAIN CONTAINING 5 SUPPORTS GLUCOSE-STIMULATED-LIPOLYSIS AND INSULIN SECRETION IN PANCREATIC BETA CELLS

Lucy Kim, Siming Liu, Spencer J. Peachee…·Yumi Imai

This study identifies ABHD5 as a critical co-activator of PNPLA2 in pancreatic beta cells, showing it supports glucose-stimulated lipolysis and insulin secretion.

DOI 10.2337/db25-1156

humanmouse

𝕏 PostBluesky

Molecular BiologybioRxivPreprintNov 17, 2024

Lipid droplet protein Perilipin 2 is critical for the regulation of insulin secretion through beta cell lipophagy and glucagon expression in pancreatic islets

Siming Liu, Israel J Wipf, Aditya Joglekar…·Yumi Imai

This study shows that PLIN2 regulates lipophagy in beta cells to prevent fatty acid accumulation in mitochondria, which impairs insulin secretion and mitochondrial function.

1 citation

humanexperimental assay

𝕏 PostBluesky