Author

Israel J Wipf

University of IowaORCID 0000-0003-1105-0786Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:Drosophila· 2 Organism:human· 1

Frequent Co-Authors

Michelle S. GiedtiD· 3 shared Tina L. TootleiD· 3 shared Aditya Joglekar· 1 shared Aidan Freshly· 1 shared Alicia ShipleyiD· 1 shared Anamika Vikram· 1 shared Beyza N. Ilerisoy· 1 shared Claudia Jun· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCell Biology

Michelle S. GiedtORCID

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3 papers

Recent·Most cited

Cell BiologyDevelopmentPeer-reviewedJul 29, 2026

ATGL-mediated lipid droplet lipolysis promotes collective migration in Drosophila

Israel J Wipf, Emma J Lowden, Michelle S. Giedt…·Tina L. Tootle

This study shows that ATGL-mediated lipid droplet lipolysis is essential for collective migration in Drosophila border cells by regulating energy production and mitochondrial function.

DOI 10.1242/dev.205486

Drosophilaexperimental assay

𝕏 PostBluesky

Cell BiologyMolecular Biology of the CellPeer-reviewedJul 9, 2025

The lipid droplet protein Jabba promotes actin remodeling downstream of prostaglandin signaling during Drosophila oogenesis

Jonathon M. Thomalla, Michelle S. Giedt, Roger P. White…·Tina L. Tootle

The paper identifies Jabba as a downstream effector of prostaglandin signaling that promotes actin remodeling during Drosophila oogenesis, revealing two distinct PG-dependent pathways for actin remodeling.

5 citations

Drosophilaexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintNov 17, 2024

Lipid droplet protein Perilipin 2 is critical for the regulation of insulin secretion through beta cell lipophagy and glucagon expression in pancreatic islets

Siming Liu, Israel J Wipf, Aditya Joglekar…·Yumi Imai

This study shows that PLIN2 regulates lipophagy in beta cells to prevent fatty acid accumulation in mitochondria, which impairs insulin secretion and mitochondrial function.

1 citation

humanexperimental assay

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