Author

Anamika Vikram

University of Iowa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Siming LiuiD· 3 shared Syreine Richtsmeier· 3 shared Yumi ImaiiD· 3 shared Aidan Freshly· 2 shared Claudia Jun· 2 shared Gianna SagonaiD· 2 shared Lucy Kim· 2 shared Spencer J. PeacheeiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

Siming LiuORCID

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Author profile →

3 papers

Recent·Most cited

ALPHA/BETA HYDROLASE DOMAIN CONTAINING 5 SUPPORTS GLUCOSE-STIMULATED-LIPOLYSIS AND INSULIN SECRETION IN PANCREATIC BETA CELLS

Lucy Kim, Siming Liu, Spencer J. Peachee, Syreine Richtsmeier, Claudia Jun, Gianna Sagona, ANAMIKA VIKRAM, Aidan Freshly, Farakh Haider, Yumi Imai

This study identifies ABHD5 as a critical co-activator of PNPLA2 in pancreatic beta cells, showing it supports glucose-stimulated lipolysis and insulin secretion.

Diabetes · May 28, 2026Peer-reviewedCell Biology

Acute Inhibition of Adipose Triglyceride Lipase by NG497 Dysregulates Insulin and Glucagon Secretion from Human Islets

Lucy B Kim, Siming Liu, Syreine Richtsmeier, Michał Górniak, Anamika Vikram, Yumi Imai

This study investigates how acute inhibition of ATGL with NG497 affects insulin and glucagon secretion from human islets, finding that chronic mechanisms dominate insulin reduction while acute inhibition reduces glucagon secretion.

Endocrinology · May 12, 2025Peer-reviewedCell Biology

Lipid droplet protein Perilipin 2 is critical for the regulation of insulin secretion through beta cell lipophagy and glucagon expression in pancreatic islets

Siming Liu, Israel J Wipf, Aditya Joglekar, Aidan Freshly, Corinne E Bovee, Lucy Kim, Syreine Richtsmeier, Spencer J. Peachee, Shayla Kopriva, Anamika Vikram, Dalal El Ladiki, Fatma S. Ilerisoy, Beyza N. Ilerisoy, Gianna Sagona, Claudia Jun, , Yumi Imai

This study shows that PLIN2 regulates lipophagy in beta cells to prevent fatty acid accumulation in mitochondria, which impairs insulin secretion and mitochondrial function.

bioRxiv · Nov 17, 2024 · PreprintMolecular Biology