Tyler J. Hill

The paper identifies feedforward and feedback mechanisms in C. elegans AFD neurons that mediate rapid thermosensory response adaptation through cGMP and calcium signaling.

The paper identifies how temperature stimuli are encoded in the gene expression of C. elegans thermosensory neurons, revealing transcriptional dynamics that drive plasticity.

The paper introduces a GFP-based cGMP sensor, WincG2, for real-time imaging of cGMP dynamics in intact C. elegans, showing its sensitivity to cGMP changes and responses to NaCl and SDS.