Author

Christian Brito-Silva

Millennium Science InitiativeORCID 0009-0000-7758-8584Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Assay:proteomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Daniel Paredes‐SabjaiD· 2 shared Marjorie Pizarro‐GuajardoiD· 2 shared Cesar E Ayala Rodriguez· 1 shared Eduardo Alberto CallegariiD· 1 shared Enzo Guerrero-ArayaiD· 1 shared F.B. GiliD· 1 shared Francisca Cid-RojasiD· 1 shared Nicolás Montes-BravoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

Daniel Paredes‐SabjaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 25, 2026

Gut complement C1q and C3 interact with Clostridioides difficile spores via CdeM and contribute to pathogenesis.

Marjorie Pizarro‐Guajardo, Christian Brito-Silva, Pablo Castro-Córdova…·Daniel Paredes‐Sabja

This study identifies complement proteins C1q and C3 as interacting with C. difficile spores via CdeM, influencing spore entry, persistence, and recurrence of infection.

DOI 10.64898/2026.09.24.753972

humanproteomics

𝕏 PostBluesky

MicrobiologyApplied and Environmental MicrobiologyPeer-reviewedMar 3, 2026

Phylogenomic analysis of the collagen-like BclA proteins in Clostridioides difficile

Francisca Cid-Rojas, Enzo Guerrero-Araya, Christian Brito-Silva…·Daniel Paredes‐Sabja

This study analyzes the conservation and variability of BclA proteins across C. difficile clades using genomic data from over 25,000 genomes, revealing clade-specific differences in bclA gene presence and structure.

1 citation

bacteria (other)whole-genome sequencing

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