Author

Mark Finazzo

The Ohio State UniversityORCID 0009-0000-8737-2699Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Bing WangiD· 2 shared Irina ArtsimovitchiD· 2 shared M. C. WahliD· 2 shared Nelly SaidiD· 2 shared Tarek HilaliD· 2 shared Daniela GjorgjevikjiD· 1 shared Tim Luca SelingeriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

Bing WangORCID

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2 papers

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedFeb 15, 2025

Transcription termination factor {rho} polymerizes under stress

Bing Wang, Nelly Said, Tarek Hilal…·Irina Artsimovitch

This study shows that Escherichia coli {rho} forms higher-order oligomers under stress, linking transcription termination to cellular physiology.

14 citationstop 3%

E. colistructural biology

𝕏 PostBluesky

BiochemistryNature CommunicationsPeer-reviewedApr 15, 2024

Sm-like protein Rof inhibits transcription termination factor Rho by binding site obstruction and conformational insulation

Nelly Said, Mark Finazzo, Tarek Hilal…·M. C. Wahl

This study identifies Rof as an inhibitor of the transcription termination factor Rho, showing it blocks Rho's activity through structural obstruction and conformational changes.

10 citations

experimental assayhost-pathogen & immune response

𝕏 PostBluesky