Author

Stefan Currie

University of GuelphORCID 0009-0000-9652-6901Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Aaron David SchimmeriD· 1 shared Adwaith B. UdayiD· 1 shared Algirdas VėlyvisiD· 1 shared Angelina S. KimiD· 1 shared Matthew S. KimberiD· 1 shared Monica M. GoncalvesiD· 1 shared Natalie ZeytuniiD· 1 shared Robert W. Harkness ViD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Aaron David SchimmerORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Mechanism of allosteric activation in human mitochondrial ClpP protease

Monica M. Goncalves, Adwaith B. Uday, Taylor J. B. Forrester, Stefan Currie, Angelina S. Kim, Yue Feng, Yulia Jitkova, Algirdas Vėlyvis, Robert W. Harkness V, Matthew S. Kimber, Aaron David Schimmer, Natalie Zeytuni, Siavash Vahidi

This study reveals the activation mechanism of human mitochondrial ClpP protease through structures showing how inhibitors induce an allosteric transition to the active state, with implications for cancer therapy.

Proceedings of the National Academy of Sciences · Apr 15, 2025Peer-reviewedBiochemistry