Angelina S. Kim

This study identifies TMEM63A as a mechanosensitive channel in lysosomes that relieves membrane tension by expelling cations and osmoticants, preventing rupture and cell death.

This study reveals the activation mechanism of human mitochondrial ClpP protease through structures showing how inhibitors induce an allosteric transition to the active state, with implications for cancer therapy.

This study investigates how nucleotide binding and Zn²⁺ affect the conformational dynamics and allosteric regulation of the YME1L protease catalytic domain.