Xinyue Liu

This study shows that primary cilia in cardiac fibroblasts promote fibrosis and impair heart function after myocardial infarction by amplifying fibrotic signaling.

This study shows that FAPs are the primary cells responding to Hedgehog signaling during muscle regeneration, and their signaling competence is critical for preventing adipogenesis, fibrosis, and promoting myofiber repair.

This study shows that intramuscular adipose tissue (IMAT) accumulation worsens limb function in PAD/CLTI, and reducing IMAT improves muscle strength and work output in mice.