Author

Yi He

University of Electronic Science and Technology of ChinaORCID 0009-0001-1642-433XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yi He3 papers · Max Planck Institute for Biological Cybernetics

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:deep learning· 2 Assay:imaging· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:metabolism & bioenergetics· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Jiankai XiaiD· 3 shared Jinhong Yan· 3 shared Kun CheniD· 3 shared Ruirong WangiD· 2 shared Zhipeng ZhangiD· 2 shared Igor I. KireeviD· 1 shared J.C. Chen· 1 shared Jeongmin Kim· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCell Biology

Jiankai XiaORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintApr 16, 2026

Light-sheet excitation-encoded volumetric spectroscopy for fast multiplexed imaging and quantitative physicochemical mapping in cells

Jinhong Yan, Jiankai Xia, Jun Liu…·Kun Chen

This paper introduces LS-ExSM, a method for fast multiplexed imaging and quantitative physicochemical mapping in cells, demonstrating six-color volumetric imaging and lipid-droplet polarity mapping.

DOI 10.64898/2026.04.14.718435

imagingdeep learning

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BiophysicsACS PhotonicsPeer-reviewedApr 16, 2025

High-throughput, unbiased single-molecule displacement mapping with deep learning reveals spatiotemporal heterogeneities in intracellular diffusivity

Jiankai Xia, Yi He, Zhipeng Zhang…·Kun Chen

This paper introduces Hi-SMdM, a high-throughput single-molecule diffusivity microscopy approach that enables unbiased mapping of spatiotemporal heterogeneities in intracellular diffusivity with improved resolution and throughput.

1 citation

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Cell BiologybioRxivPreprintApr 3, 2025

Excitation Spectral Phasor Microscopy (ExSPM) unveils spatiotemporal heterogeneities in polarity of intracellular lipid droplets

Jiayi Liu, Mingxuan Tang, Rui Yan…·Kun Chen

ExSPM reveals spatiotemporal heterogeneities in lipid droplet polarity, showing dynamics and pathway-specific kinetics of lipid metabolism.

3 citations

fluorescence / live-cell microscopymicroscopy & imaging analysis

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