Marika Majerova

This study uses ultrahigh-throughput screening to identify mutations in dehalogenases that modulate substrate access and binding, revealing distal functional effects on enzyme dynamics.

This study determines the crystal structures and dynamical behavior of an ancestral ABH-fold enzyme, revealing molecular features that enabled the transition from hydrolytic to oxygenolytic catalysis.

The paper identifies the origin of a luciferase gene from haloalkane dehalogenases in brittle stars and shows parallel evolution of bioluminescence across distant species.