Ellen L. Kan

This paper develops a vascularized liver microphysiological system to model hepatic insulin resistance and monocyte infiltration, showing altered metabolism, vascular changes, and immune cell recruitment.

This paper develops a label-free imaging platform to study nucleolar dynamics and metabolic shifts in tissues, revealing NADH depletion under nucleolar stress and progesterone-induced changes in endometrial organoids.

This paper develops a vascularized tumor model to study TAM recruitment and evaluates a multispecific antibody's effect on monocyte migration and TAM repolarization.