Author
The Netherlands Cancer InstituteORCID 0009-0001-3282-793XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Rianne G. Bouma, Willem-Jan de Leeuw, Aru Z. Wang…·Joke M. M. den Haan
This study shows that DOT1L influences dendritic cell subset development and antigen presentation by modulating histone H3K79 methylation.
Muddassir Malik, Willem-Jan de Leeuw, Muhammad Assad Aslam…·Fred van Leeuwen
This study shows that DOT1L maintains CD8 T cell identity and restricts their cytotoxic potential by preventing NK-cell features and enhancing anti-tumor reactivity.
Kelly Warmink, Philip Lijnzaad, Stephanie A Schubert…·Claudia Y. Janda
This study investigates dexamethasone-induced bone toxicity in developing bones using single-cell transcriptomics in mice, revealing reduced osteoblast and chondrocyte populations and disrupted B cell development.