BioengineeringNature BiotechnologyPeer-reviewed
High-plex spatial RNA imaging in one round with conventional microscopes using color-intensity barcodes
Tianyi Chang, Shihui Zhao, Kunyue Deng…·Yanyi Huang
This paper introduces PRISM, a method for high-plex spatial RNA imaging using color intensity barcodes, validated across multiple tissues and showing the role of CAFs in tumor microenvironments.