Molecular BiologyiSciencePeer-reviewed
DNA-encoded Library Screening Uncovers Potent DNMT2 Inhibitors Targeting a Cryptic Allosteric Binding Site
Ariane F. Frey, Merlin Schwan, Annabelle Carolin Weldert…·Fabian Barthels
This study identifies potent DNMT2 inhibitors through DNA-encoded library screening, revealing a cryptic allosteric binding site and optimizing an inhibitor with low nanomolar affinity.
4 citations