Author

Nir Strugo

Technion – Israel Institute of TechnologyORCID 0009-0001-6706-5197Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:DNA methylation· 1 Organism:yeast· 1

Frequent Co-Authors

Ariel KaplaniD· 2 shared Carmit Burstein· 2 shared Moshe GoldsmithiD· 2 shared Noam NagoiD· 2 shared Hadeel Khamis· 1 shared Philippa MelamediD· 1 shared Sergei RudnizkyiD· 1 shared Sk Saddam Hossain· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersBiophysics

Ariel KaplanORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJul 30, 2026

Tunable kinetic destabilization governs RNA polymerase passage through a DNA-bound transcription factor

Noam Nago, Sergei Rudnizky, Nir Strugo…·Ariel Kaplan

The paper shows DNA-bound Egr-1 delays RNA polymerase elongation through kinetic destabilization, with CpG methylation reducing this delay.

DOI 10.64898/2026.07.29.741407

DNA methylationexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintMay 23, 2025

Intrinsically disordered regions facilitate Msn2 target search to drive promoter selectivity

Nir Strugo, Carmit Burstein, Sk Saddam Hossain…·Ariel Kaplan

This study shows that intrinsically disordered regions in Msn2 enhance DNA binding and promoter selectivity through non-specific association and one-dimensional diffusion.

1 citation

yeastexperimental assay

𝕏 PostBluesky