Author

Sara E. Cahill

University of Massachusetts Chan Medical SchoolORCID 0009-0001-9648-5326Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Fiachra HumphriesiD· 2 shared Laurel Stine· 2 shared Liraz Shmuel-GaliaiD· 2 shared Abigail Sondrini· 1 shared Evelyn A. Kurt‐JonesiD· 1 shared G. Scott PesiridisiD· 1 shared John BertiniD· 1 shared Joshi M. RamanjuluiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Fiachra HumphriesORCID

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2 papers

Recent·Most cited

ImmunologyThe Journal of ImmunologyPeer-reviewedJul 28, 2026

Non-canonical TLR signaling restricts cytosolic LPS detection.

Shriram Ramani, Sara E. Cahill, Matthew Finnegan…·Fiachra Humphries

This study identifies MARCO as a decoy LPS sensor regulated by non-canonical TLR signaling, which restricts inflammasome activation and prevents excessive inflammation.

DOI 10.1093/jimmun/vkag141.1471

mouseproteomics

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ImmunologyProceedings of the National Academy of SciencesPeer-reviewedMay 27, 2025

Alternative cGAS signaling promotes Herpes simplex encephalitis

Liraz Shmuel-Galia, Zhaozhao Jiang, Laurel Stine…·Fiachra Humphries

This study identifies an alternative cGAS signaling pathway independent of cGAMP that promotes neutrophil recruitment and viral dissemination in herpes simplex encephalitis.

3 citations

humanexperimental assay

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