Ronald Challita

An Implantable Wireless Battery-Free Spatially Selective Vagus Nerve Stimulator

This paper develops a wireless battery-free implantable device for selective vagus nerve stimulation, demonstrating reduced off-target effects in pigs and a human trial.

TRPV1-cardiac afferent ablation after completed myocardial infarction prevents arrhythmogenic remodeling

This study shows that ablating cardiac TRPV1 afferents after completed myocardial infarction reduces arrhythmogenic remodeling and improves cardiac function.

Anatomical and functional organization of cardiac fibers in the porcine cervical vagus nerve allows spatially selective efferent neuromodulation

This paper demonstrates spatially-selective vagus nerve stimulation (sVNS) can target cardiac efferent fibers to decrease heart rate without stimulating afferent-related reflexes, improving precision and efficacy of neuromodulation for cardiac disease.