ACAD10 encodes two orphan enzymes in the ether lipid biosynthetic and salvage pathways
James S. Ye, Elena Purlyte, Víctor A. López, Jericha Mill, Lexus Tatge, Thomas Kizzar, Dominique A. Baldwin, Edrees H. Rashan, Juhee Kim, David J. Pagliarini, Diana R. Tomchick, Krzysztof Pawłowski, Peter M. Douglas, Judith Simcox, Vincent S. Tagliabracci
This study identifies ACAD10 as encoding two enzymes involved in ether lipid biosynthesis and salvage, linking them to type 2 diabetes risk.
bioRxiv · Sep 10, 2025 · PreprintBiochemistry