Mickaël Maziero

The porin MspA is a phage-specific determinant of mycobacteriophage infection

This study identifies outer membrane porins as phage-specific determinants of mycobacterial susceptibility through a CRISPRi screen in Mycobacterium smegmatis.

Development of inducible genetic systems to finely tune efficacy of InhA-targeting anti-tuberculous drugs

This paper develops CRISPRi-based inducible systems to fine-tune antibiotic susceptibility in Mycobacterium tuberculosis by targeting key genes involved in drug activation.

Mycobacterial cell division arrest and smooth-to-rough envelope transition using CRISPRi-mediated genetic repression systems

This paper describes a CRISPRi-based protocol to assess gene silencing and envelope transitions in Mycobacterium smegmatis as a model for NTM pathogenesis.

A toxin/antitoxin system targeting the replication sliding-clamp induces competence in Streptococcus pneumoniae.

This study identifies a toxin-antitoxin system in Streptococcus pneumoniae that induces competence by causing replicative stress and triggering the comCDE operon.