Michael A. DeJesus

This study identifies outer membrane porins as phage-specific determinants of mycobacterial susceptibility through a CRISPRi screen in Mycobacterium smegmatis.

The paper identifies Rv2571c as a mycobacterial ion channel that mediates pyrazinamide resistance by regulating cytoplasmic acidification.

This study identifies a candidate transmission survival genome of Mycobacterium tuberculosis by exposing it to model aerosol fluid and analyzing gene contributions to survival during transmission.

This paper introduces CRISPRi-DR, a dose-response model to analyze chemical-genetic interactions in CRISPRi screens, showing improved precision over existing methods.

This paper introduces a statistical method using Zero-Inflated Negative Binomial regression to identify genes with significant variability in insertion counts across multiple conditions in TnSeq data.