Pedro Rifes

Decoding morphogen patterning of human neural organoids with a multiplexed single-cell transcriptomic screen

The paper uses a multiplexed single-cell transcriptomic screen to study how morphogen cues affect regional specification in human neural organoids, finding that timing, concentration, and combination of morphogens strongly influence cell type and regional composition.

Mapping early patterning events in human neural development usingan in-vitro microfluidic stem cell model

The paper uses a microfluidic stem cell model to study early human neural patterning, identifying regional specification and fate determination during the epiblast stage.

Fibronectin-dependent tissue mechanics regulate the translation of segmentation clock oscillations into periodic somite formation

The paper investigates how fibronectin-dependent tissue mechanics influence the translation of segmentation clock gene oscillations into periodic somite formation in the presomitic mesoderm.