Author

Alex Westbrook

Centre National de la Recherche ScientifiqueORCID 0009-0002-1771-7617Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:yeast· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Research Focus:sequence-to-function modeling· 1

Frequent Co-Authors

Etienne RouthieriD· 2 shared Julien MozziconacciiD· 2 shared Agnès ThierryiD· 1 shared Alexandra JoubertiD· 1 shared Amaury BignaudiD· 1 shared Angela TaddeiiD· 1 shared Astrid Lancrey· 1 shared Aurèle PiazzaiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSynthetic Biology

Etienne RouthierORCID

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2 papers

Recent·Most cited

Synthetic BiologyNucleic Acids ResearchPeer-reviewedMay 29, 2024

In silico design of DNA sequences for in vivo nucleosome positioning

Etienne Routhier, Alexandra Joubert, Alex Westbrook…·Julien Mozziconacci

The paper designs synthetic DNA sequences for in vivo nucleosome positioning in yeast using a kinetic Monte Carlo framework combined with deep learning predictions.

8 citations

yeastDNA methylation

𝕏 PostBluesky

GeneticsbioRxivPreprintDec 21, 2022

Exogenous chromosomes reveal how sequence composition drives chromatin assembly, activity, folding and compartmentalization

Christophe Chapard, Léa Meneu, Jacques Serizay…·Romain Koszul

This study shows that bacterial chromosomes can undergo chromatin assembly, activity, looping, and compartmentalization in yeast, driven by their sequence composition.

11 citations

yeastDNA methylation

𝕏 PostBluesky