Léa Meneu

This study identifies a CST complex-mediated post-resection NHEJ repair pathway that promotes intermediate deletions while preventing larger deletions and rearrangements.

The paper identifies how the 2μ plasmid in yeast binds to inactive chromosomal regions through nucleosome signals and RNA Pol II depletion, revealing a stable and rapid tethering mechanism.

This study shows that bacterial chromosomes can undergo chromatin assembly, activity, looping, and compartmentalization in yeast, driven by their sequence composition.