Nisreen Ghanem

This study investigates how stromal cells and macrophages interact during mycobacterial infection, revealing their roles in shaping immune responses and granuloma formation.

This study shows that M-CSF drives alveolar macrophage plasticity during development and CMV infection, increasing ISG expression and modulating infection susceptibility.

This study maps the postnatal differentiation trajectories of dendritic epidermal T cells and Langerhans cells in mice, showing they develop independently of each other and microbial colonization.

This study shows neonatal BCG vaccination expands IL-17/IL-22-producing γδ T cells, mediates protection against TB, and induces a microbiome signature linked to gut-lung axis immunity.

This study shows that dermal macrophages can maintain functional diversity without monocyte replenishment, but require monocytes during bacterial infections.