Author

Katrin Kierdorf

University of FreiburgORCID 0000-0002-9272-4780Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:Drosophila· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Julia KolteriD· 3 shared Philipp HennekeiD· 3 shared Clarissa-Laura Döring· 2 shared Nisreen GhanemiD· 2 shared Philipp AktoriesiD· 2 shared S SagariD· 2 shared Sebastian BaaschiD· 2 shared Aakriti SinghiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersImmunology

Julia KolterORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

M-CSF drives alveolar macrophage plasticity during development and cytomegalovirus infection

Sebastian Baasch, Alina Nelipovich, Zhibek Zhumadilova, Julia Henschel, Nisreen Ghanem, Clarissa-Laura Döring, Philipp Aktories, Leonhard Wagner, Agnibesh Dey, Domien Vanneste, Martin Helmstädter, Katrin Kierdorf, Julia Kolter, Gabriele Lubatti, S Sagar, , Philipp Henneke

This study shows that M-CSF drives alveolar macrophage plasticity during development and CMV infection, increasing ISG expression and modulating infection susceptibility.

bioRxiv · Apr 14, 2026 · PreprintImmunology

Postnatal Maturation of Dendritic Epidermal T Cells and Langerhans Cells Follows Distinct Differentiation Trajectories Independent of Microbiota

David Obwegs, Alexander Oschwald, Lara M. Koetter, Cylia Crisand, Sidney Doerr, Kerstin Bruder, Solveig Runge, Nisreen Ghanem, Vidmante Fuchs, Marleen Eckert, Julia Kolter, Daniel Erny, Marco Prinz, Susana Minguet, Wolfgang W A Schamel, , S Sagar

This study maps the postnatal differentiation trajectories of dendritic epidermal T cells and Langerhans cells in mice, showing they develop independently of each other and microbial colonization.

bioRxiv · Apr 7, 2026 · PreprintImmunology

Sensory neurons shape macrophage identity via TGF-β signalling

Julia Kolter, Clarissa-Laura Döring, Samah Sarout, Sebastian Baasch, Lloyd Steele, Reem Alsumati, Gabriel Victor Lucena da Silva, Conceição Elidianne Aníbal Silva, Isadora Marques Paiva, Zohreh Mansoori Moghadam, Vitka Gres, Florens Lohrmann, Philipp Aktories, Theresa Buchegger, Mitchell Bijnen, , Philipp Henneke

This study identifies TGF-β as a key mediator of macrophage specialization in the skin through interaction with sensory nerves.

Immunity · Sep 5, 2025Peer-reviewedImmunology

PDK-1/S6K and mTORC1 bypass systemic growth restrictions to promote regeneration

Ananthakrishnan Vijayakumar Maya, Lena Neuhaus, Liyne Nogay, Aakriti Singh, Lara Heckmann, Isabelle Grass, Joerg Martin Buescher, Katrin Kierdorf, Anne-Kathrin Classen

The paper identifies a metabolic pathway involving Pdk1/S6K and mTORC1 that allows regenerating tissues to bypass systemic growth restrictions induced by inflammation.

bioRxiv · Aug 5, 2024 · PreprintDevelopmental Biology

Muscle function and homeostasis require macrophage-derived cytokine inhibition of AKT activity in Drosophila

Katrin Kierdorf, Fabian Hersperger, Jessica Sharrock, Crystal M. Vincent, Pınar Ustaoğlu, Jiawen Dou, Attila Gyoergy, Olaf Groß, Daria Elisabeth Siekhaus, Marc Dionne

eLife · Jan 16, 2020Peer-reviewedDevelopmental Biology