Julia Kolter

Streptococcal meningoencephalitis dynamically shapes developmental monocyte and macrophage trajectories in the CNS

This study shows that streptococcal meningoencephalitis alters monocyte and macrophage dynamics in the dura by shifting their origin from skull bone marrow to peripheral sources and increasing MDP-Mo-derived cells.

Crosstalk between Stromal Cells and Macrophages Shapes Host Immunity to Mycobacteria

This study investigates how stromal cells and macrophages interact during mycobacterial infection, revealing their roles in shaping immune responses and granuloma formation.

M-CSF drives alveolar macrophage plasticity during development and cytomegalovirus infection

This study shows that M-CSF drives alveolar macrophage plasticity during development and CMV infection, increasing ISG expression and modulating infection susceptibility.

Postnatal Maturation of Dendritic Epidermal T Cells and Langerhans Cells Follows Distinct Differentiation Trajectories Independent of Microbiota

This study maps the postnatal differentiation trajectories of dendritic epidermal T cells and Langerhans cells in mice, showing they develop independently of each other and microbial colonization.

Mycobacterial infection uncovers plasticity of Kupffer cells

The paper investigates KC plasticity in mycobacterial infections, finding that KClow cells derived from bona fide KCs exhibit unique antimycobacterial activity and adaptability.

Macrophage renewal in the small intestine governs early-life control of streptococci

This study shows that small intestine macrophage dynamics control GBS colonization and invasion in infant mice, with region-specific responses to the pathogen.

Neonatal BCG Vaccination Engages the Vasculature to Elicit γδ T Cell-Mediated Protection against Tuberculosis

This study shows neonatal BCG vaccination expands IL-17/IL-22-producing γδ T cells, mediates protection against TB, and induces a microbiome signature linked to gut-lung axis immunity.

Sensory neurons shape macrophage identity via TGF-β signalling

This study identifies TGF-β as a key mediator of macrophage specialization in the skin through interaction with sensory nerves.

Tissue imprinting defines functional mosaic of dermal macrophages

This study shows that dermal macrophages can maintain functional diversity without monocyte replenishment, but require monocytes during bacterial infections.