Wenbo Zhang

This paper identifies that N1 cassette-lacking NMDA receptors mediate ketamine's antidepressant effect by remaining blocked during neuronal firing.

This study shows that Beclin 1 inhibition exacerbates pain hypersensitivity in male mice but not females, suggesting sex-specific therapeutic targets for pain management.

This study identifies hyperexcitable network events called reverberating super bursts in MECP2 null neuronal networks and shows they can be mitigated by a calcium chelator.

This study examines the effects of MECP2 mutations on neuronal and network phenotypes in human stem cell-derived excitatory neurons, showing a spectrum of morphological, electrophysiological, and circuitry changes based on mutation severity.