Author
Columbia University Irving Medical CenterORCID 0009-0002-2617-268XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Amber N. Wolabaugh, Vrushali V. Agashe, Zicheng Wang…·Megan Sykes
This paper develops a human immune system mouse model to study SARS-CoV-2 dissemination and immune responses, finding that human T cells suppress innate immunity and allow viral persistence.
Giorgia Zanetti, Mateusz Legut, Austin Chen…·Mohsen Khosravi Maharlooei
This paper presents a CRISPR-based platform that removes endogenous TCRα/β chains to enhance transgenic TCR function and safety in T-cell therapies and autoimmune modeling.
Mohsen Khosravi-Maharlooei, Andrea Vecchione, Nichole M. Danzl…·Megan Sykes
The paper shows that PD-1+CD4+ Tfh-like and Tph-like cells in human immune system mice drive autoimmune disease, with disease progression linked to HLA-restricted T cell-APC interactions.