BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Revised Mechanism of Hydroxyurea Induced Cell Cycle Arrest and an Improved Alternative
Alisa E. Shaw, Mattias N. Mihelich, Jackson Whitted…·Grant D. Schauer
This paper revises the mechanism of hydroxyurea-induced cell cycle arrest in yeast, showing it is ROS-mediated rather than Mrc1-dependent, and introduces an improved alternative to HU called RNR-deg.
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