BioengineeringBiomaterialsPeer-reviewed
Synthetic peptide hydrogels as a model of the bone marrow niche demonstrate efficacy of a combined CRISPR-CAR T-cell therapy for acute myeloid leukaemia
W. Sebastian Doherty-Boyd, Penelope M. Tsimbouri, Vineetha Jayawarna…·Hannah Donnelly
The paper develops a synthetic BM niche model to test CRISPR-CAR T-cell therapy for AML, showing its efficacy in a human-like environment.
3 citations