Author

Hannah Donnelly

University of GlasgowORCID 0000-0002-5154-9971Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1

Frequent Co-Authors

Manuel Salmerón‐SáncheziD· 2 shared Matthew John DalbyiD· 2 shared Peter S. YoungiD· 2 shared Vineetha JayawarnaiD· 2 shared Abhimanyu KiraniD· 1 shared Adam G. WestiD· 1 shared Aline F. Miller· 1 shared Amy L. ShergoldiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioengineering

Manuel Salmerón‐SánchezORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Bioengineered bone marrows that can support stem cells and remodel to mimic human disease metabolism and chemotherapeutic effects

Yinbo Xiao, Savvas Ioannou, Monica P. Tsimbouri, Xiang Li, Oana Dobre, Sara Trujillo, Mark Robert Sprott, Mariana Azevedo Gonzalez‐Oliva, Vineetha Jayawarna, Massimo Vassalli, Ewan A. Ross, Mhairi Copland, Peter S. Young, Dominic R. M. Meek, Manuel Salmerón‐Sánchez, , Matthew John Dalby

The paper develops a bioengineered bone marrow model that supports stem cells and mimics disease metabolism and chemotherapy effects, showing enhanced taurine metabolism and chemotherapy response.

bioRxiv · Dec 5, 2025 · PreprintBioengineering

Macrophage chemotaxis steered by complex self-generated gradients of complement C5a

Abhimanyu Kiran, Peter A. Thomason, David M. Versluis, Peggy Paschke, Hannah Donnelly, Luke Tweedy, Sérgio Lilla, Isabel Bravo-Ferrer, Amy L. Shergold, R Devlin, Ed Roberts, Robert H. Insall

This study shows mouse and human macrophages use self-generated C5a gradients for chemotaxis, with distinct degradation mechanisms and optimal concentrations.

bioRxiv · Nov 5, 2025 · PreprintImmunology

Synthetic peptide hydrogels as a model of the bone marrow niche demonstrate efficacy of a combined CRISPR-CAR T-cell therapy for acute myeloid leukaemia

W. Sebastian Doherty-Boyd, Penelope M. Tsimbouri, Vineetha Jayawarna, Matthew Walker, Aqeel F. Taqi, Niall Mahon, R.M. Dominic Meek, Peter S. Young, Aline F. Miller, Adam G. West, Manuel Salmerón‐Sánchez, Matthew John Dalby, Hannah Donnelly

The paper develops a synthetic BM niche model to test CRISPR-CAR T-cell therapy for AML, showing its efficacy in a human-like environment.

Biomaterials · Oct 26, 2025Peer-reviewedBioengineering