PhysiologyThe FASEB JournalPeer-reviewed
Overexpression of enhanced yellow fluorescent protein fused with Channelrhodopsin-2 causes contractile dysfunction in skeletal muscle
Syeda N. Lamia, Carol S. Davis, Peter C. D. Macpherson…·Megan Leigh Killian
This study shows that overexpressing ChR2-EYFP in skeletal muscle causes contractile dysfunction, while ChR2-only mice show normal function, highlighting the need for alternative optogenetic models.
2 citations