A double-blinded, placebo-controlled field trial of an OspA-based oral reservoir targeted vaccine against Borrelia burgdorferi
Amy Schwartz, Ferney Henao-Ceballos, Kathryn Arnold, Julia E. Poje, Max Waugh, Greg Joyner, José F. Azevedo, Tyler Baccam, Eric Kontowicz, Kurayi Mahachi, Paige Witucki, Suman Kundu, Nisha Nair, Felix M. Pabon‐Rodriguez, Grant Brown, , Maria J. C. Gomes-Solecki
A field trial tested an OspA-based oral vaccine targeting reservoir mice, showing reduced tick infection rates and increased antibody levels in vaccinated mice.
npj Vaccines · May 11, 2026Peer-reviewedMicrobiology