Author

Victoria F. Gomerdinger

Broad InstituteORCID 0000-0003-1122-0482Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:proteomics· 1

Frequent Co-Authors

Paula Therese HammondiD· 3 shared Aidan KindoppiD· 2 shared Apoorv ShankeriD· 2 shared Gil Covarrubias· 2 shared Ivan Susin PiresiD· 2 shared Julia TreeseiD· 2 shared Justin A. KaskowiD· 2 shared Margaret M. BillingsleyiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersBioengineering

Paula Therese HammondORCID

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3 papers

Recent·Most cited

Engineering nanoparticle surface chemistry for antigen-presenting cell targeting improves specificity and safety of TLR3 agonist cancer immunotherapy

Victoria F. Gomerdinger, Cassandra Parada, Andrea Li, Aidan Kindopp, Justin A. Kaskow, Eva Cai, Julia Treese, Ivan Susin Pires, Apoorv Shanker, Gil Covarrubias, Alexander D. Stoneman, Magalie Boucher, Paula Therese Hammond

This paper develops a nanoparticle platform to target TLR3 agonist to antigen-presenting cells, improving cancer immunotherapy safety and efficacy by reducing systemic toxicity and enhancing tumor targeting.

bioRxiv · Jun 25, 2026 · PreprintBioengineering

A Multivalent Peptide-Polymer Conjugate Material Mimics STING to Therapeutically Activate Innate Immune Signaling

Justin A. Kaskow, Julia Treese, Anita Gaenko, Victoria F. Gomerdinger, Zhi Kai Tio, Margaret M. Billingsley, Aidan Kindopp, Paula Therese Hammond

This paper develops a multivalent peptide-polymer conjugate that mimics STING to activate innate immune signaling and shows tumor regression in ovarian cancer models.

bioRxiv · Mar 26, 2026 · PreprintBioengineering

'Target-and-release' nanoparticles for effective immunotherapy of metastatic ovarian cancer

Ivan Susin Pires, Gil Covarrubias, Victoria F. Gomerdinger, Coralie M. Backlund, Eduardo Nombera Bueno, Margaret M. Billingsley, Mae L. Pryor, Apoorv Shanker, Ezra Gordon, Shengwei Wu, Andrew J. Pickering, Mariane B. Melo, Heikyung Suh, Darrell J. Irvine, Paula Therese Hammond

This study develops IL-12-loaded nanoparticles that enhance immunotherapy for metastatic ovarian cancer by promoting T cell accumulation and sensitizing tumors to checkpoint inhibitors.

Nature Materials · Oct 31, 2025Peer-reviewedBioengineering